Fw: Major Breakthrough in the Fight Against Cholera

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2011年3月2日 星期三,OneWorld Health <info@oneworldhealth.org> 寫道﹕

寄件人: OneWorld Health <info@oneworldhealth.org>
主題: Major Breakthrough in the Fight Against Cholera
收件人: incubator.hou@gmail.com
日期: 2011年3月2日,星期三,上午7:01

 

Institute for OneWorld Health

Dear Houghton,

I wanted to share some exciting news! 

OneWorld Health announced today a major breakthrough in the fight against cholera and other secretory diarrheas.  This major milestone has potential to save millions of neglected lives worldwide.

The Food and Drug Administration (FDA) granted iOWH permission to begin phase 1 trials for iOWH032, a drug to treat secretory diarrhea. This is the first submission of an Investigational New Drug application for a completely new chemical entity by a non-profit of this size to receive such rapid FDA clearance, and it could be the first synthetic drug of its kind for diarrheal diseases.

This new drug, whose development was funded by the Bill & Melinda Gates Foundation, reduces fluid loss and is designed to be used in conjunction with oral rehydration therapy (ORT). This treatment would provide faster relief of diarrhea symptoms and encourage wider adoption of ORT resulting in reduction of mortality rate and improvement of quality of life.

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